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I tried a payroll service my first year in business. It was expensive and impersonal. The next year I hired a part time bookeeper as a subcontractor. She does payroll, deals with all quarterly taxes, gets yearly tax info ready for the accountant, reconciles and pays all the bills. balances the checkbook (which is pretty easy in quickbooks), and more. She knows more about my finantial situation on a daily basis than I do (Luckily she is trustworthy) She costs me about $70 a week. Not bad considering that it would take me 4-6 hours a week to do all that myself. Ionly see her about once every two months. We do 90% of our business through the mail and e-mail.